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Robarts Research Institute

User's Published Papers (61)

The following is a list of microarray papers published by our users:

 

2010 (2)

 

Johansen CT, Wang J, Lanktree MB, Cao H, McIntyre AD, Ban MR, Martins RA, Kennedy BA, Hassell RG, Visser ME, Schwartz SM, Voight BF, Elosua R, Salomaa V, O'Donnell CJ, Dallinga-Thie GM, Anand SS, Yusuf S, Huff MW, Kathiresan S, Hegele RA. Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia. Nat Genet. 2010 Aug; 42(8):684-7.

Andrews J, Kenette W, Pilon J, Hodgson A, Tuck AB, Chambers AF, Rodenhiser DI. Multi-platform whole-genome microarray analyses refine the epigenetic signature of breast cancer metastasis with gene expression and copy number. PLoS One. 2010 Jan 13;5(1):e8665

 

2009 (13)

Lanktree MB, Fantus IG, Hegele RA. Triple X syndrome in a patient with lipodystrophy discovered using a high-density oligonucleotide microarray: a case report. J Med Case Reports . 2009 Aug 12;3:8867.

 

Pandit TS, Kennette W, Mackenzie L, Zhang G, Al-Katib W, Andrews J, Vantyghem SA, Ormond DG, Allan AL, Rodenhiser DI, Chambers AF, Tuck AB. Lymphatic metastasis of breast cancer cells is associated with differential gene expression profiles that predict cancer stem cell-like properties and the ability to survive, establish and grow in a foreign environment. Int J Oncol. 2009 Aug;35(2):297-308.

 

Cavanagh PC, Dunk C, Pampillo M, Szereszewski JM, Taylor JE, Kahiri C, Han V, Lye S, Bhattacharya M, Babwah AV. Gonadotropin-releasing hormone-regulated chemokine expression in human placentation. Am J Physiol Cell Physiol. 2009 Jul;297(1):C17-27.

 

Dong S, Qutob D, Tedman-Jones J, Kuflu K, Wang Y, Tyler BM, Gijzen M. The Phytophthora sojae avirulence locus Avr3c encodes a multi-copy RXLR effector with sequence polymorphisms among pathogen strains. PLoS ONE. 2009;4(5):e5556.

 

Qutob D, Tedman-Jones J, Dong S, Kuflu K, Pham H, Wang Y, Dou D, Kale SD, Arredondo FD, Tyler BM, Gijzen M. Copy number variation and transcriptional polymorphisms of Phytophthora sojae RXLR effector genes Avr1a and Avr3a. PLoS ONE. 2009;4(4):e5056.

 

Edmondson AC, Brown RJ, Kathiresan S, Cupples LA, Demissie S, Manning AK, Jensen Mk, Rimm EB, Wang J, Rodriques A, Bamba V, Khetarpal SA, Wolfe ML, Derohannessian S, Li M, Reilly MP, Aberle J, Evans D, Hegele RA, Rader DJ. Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans. J Clin Invest. 2009 Apr;119(4):1042-50

 

Roscoe WA, Welsh ME, Carter DE, Karlik SJ. VEGF and angiogenesis in acute and chronic MOG(35-55) peptide induced EAE. J Neuroimmunol. 2009 Apr 30:209(1-2):6-15.

 

Gris P, Tighe A, Thawer S, Hemphill A, Oatway M, Weaver L, Dekaban GA, Brown A. Gene expression profiling in anti-CD11d mAb-treated spinal cord-injured rats. J Neuroimmunol. 2009 Apr 30;209(1-2):104-13.

 

Rockel JS, Bernier SM, Leask A. Egr-1 inhibits the expression of extracellular matrix genes in chondrocytes by TNFalpha-induced MEK/ERK signalling. Arthitis Res Ther. 2009;11(1):R8.

 

Attur MG, Palmer GD, Al-Mussawir HE, Dave M, Teixeira CC, Rifkin DB, Appleton CTG, Beier F, Abramson SB. F-spondin, a neuroregulatory protein, is up-regulated in osteoarthritis and regulates cartilage metabolism via TFG- b activation. Faseb J. 2009 Jan; 23:79-89.

 

Estilo CL, O-Charoenrat P, Talbot S, Socci N, Carlson DL, Ghossein R, Williams T, Yonekawa Y, Ramanathan Y, Boyle JO, Kraus DH, Patel S, Shaha AR, Wong RJ, Huryn JM, Shah JP, Singh B. Oral tongue cancer gene expression profiling: Identification of novel potential prognosticators by oligonucleotide microarray analysis. BMC Cancer 2009 Jan 12;9(1):11

 

Shi-wen X, Parapuram S, Pala D, Chen Y, Carter DE, Eastwood M, Denton CP, Abraham DJ, Leask A. Requirement of transforming growth factor Beta-activated kinase 1 for transforming growth factor Beta-induced a-smooth muscle actin expression and extracellular matrix contraction in fibroblasts. Arthritis Rheum. 2009 Jan; 60(1):234-41.

 

Singh SM, Castellani CA, O'Reilly RL. Copy number variation showers in schizophrenia: an emerging hypothesis. Mol Psychiatry. 2009 Jan 13.

 

2008 (14)

 

Lanktree MB, Hegele RA. Copy number variation in metabolic phenotypes. Cytogenet Genome Res. 2008;123(1-4):169-75.

 

Levy MA, Fernandes AD, Tremblay DC , Seah C, Berube NG. The SWI/SNF protein ATRX co-regulates pseudoautosomal genes that have translocated to autosomes in the mouse genome. BMC Genomics. 2008 Oct; 9(468).

 

Solomon LA, Berube NG, Beier F. Transcriptional regulators of of chondrocyte hypertrophy. Birth Defects Res C. 2008; 84:123-130.

 

Yang K, Guan H, Arany E, Hill DJ, Cao X. Neuropeptide Y is produced in visceral adipose tissue and promotes proliferation of adipocyte precursor cells via the Y1 receptor. Faseb J. 2008 July; 22: 2452-64.

 

Stuart HC, Messenberg A, Joshi B, Underhill TM, Moukhles H, Nabi IR. Localized Rho GTPase regulates RNA dynamics and compartmentalization in tumour cell protrusions. J Biol Chem. 2008 Dec. 12;;283(50):34785-95.

 

Thillainadesan G, Isovic M, Loney E, Andrews J, Tini M, Torchia J. Genome analysis identifies the p15ink4b tumour suppressor as a direct target of the ZNF217Corest complex. Mol Cell Biol. 2008 Oct;28(19):6066-77.

 

Rodenhiser DI, Andrews J, Kennette W, Sadikovic B, Mendlowitz A, Tuck AB, Chambers AF. Epigenetic mapping and functional analysis in a breast cancer metastasis model using whole-genome promoter tiling arrays. Breast Cancer Res. 2008;10(4):R62

 


Dahn A, Saunders S, Hammond JA, Carter D, Kirjavainen P, Anukam K, Reid G
. Effect of bacterial vaginosis, Lactobacillus and Premarin estrogen replacement therapy on vaginal gene expression changes. Microbes Infect. 2008 May 17;371(9625):1685-94.

 


Kennedy L, Shiw-Wen X, Carter DE, Abraham DJ, Leask A
. Fibroblast adhesion results in the induction of a matrix remodeling gene expression program. Matrix Biol. 2008 May;27(4):274-81.

 


Pala D, Kapoor M, Woods A, Kennedy L, Liu S, Chen S, Bursell L, Lyons KM, Carter DE, Beier F, Leask A.
FAK/SRC suppresses early chondrogenesis: central role of CCN2. J Biol Chem. 2008 Apr 4:283(14):9239-47.

 


Chen Y, Leask A, Abraham DJ, Pala D, Shiwen X, Khan K, Liu S, Carter DE, Wilcox-Adelman S, Goetinck P, Denton CP, Black CM, Pitsillides AA, Sarraf CE, Eastwood M.
Heparan sulfate-dependent ERK activation contributes to the overexpression of fibrotic proteins and enhanced contraction by scleroderma fibroblasts. Arthritis Rheum. 2008 Feb; 58(2):577-85.

 

Kirjavainen PV, Laine RM, Carter DE, Hammond J, Reid G. Expression of anti-microbial defense factors in vaginal mucosa following exposure to Lactobacillus rhamnosus GR-1. International Journal of Probiotics and Prebiotics. [Accepted Feb. 24, 2008]

 


Sadikovic B, Andrews J, Carter D, Robinson J, Rodenhiser DI
. Genome-wide H3K9 histone acetylation profiles are altered in benzopyrene treated MCF7 breast cancer cells. J. Biol. Chem. 2008 Feb 15;283(7):4051-60.

 

Viswanathan K, Richardson J, Togonu-Bickersteth B, Dai E, Liu L, Vatsya P, Sun YM, Yu J, Munuswamy-Ramunujam G, Baker H, Lucas AR. Myxoma viral serpin, Serp-1, inhibits human monocyte adhesion through regulation of actin-binding protein filamin B. J Leukoc Biol. 2008 Dec 3. [Epub ahead of print]

 

2007 (10)

Sadikovic B, Andrews J, Rodenhiser DI. DNA methylation analysis using CpG microarrays is impaired by benzopyrene exposed cells. Toxicol Appl Pharmacol. 2007 Dec 15;225(3):300-309.

 

Chen S, McLean S, Carter DE, Leask A. The gene expression profile induced by Wnt 3a in NIH 3T3 fibroblasts. J Cell Commun Signal. 2007 Dec;1(3-4):175-83.

 

Gris P, Tighe A, Levin D, Sharma R, Brown A. Transcriptional regulation of scar gene expression in primary astrocytes. Glia. 2007 Aug 15;55(11):1145-55.

 

Shi-Wen X, Renzoni EA, Kennedy L, Howat S, Chen Y, Pearson JD, Bou-Gharios G, Dashwood MR, du Bois RM, Black CM, Denton CP, Abraham DJ, Leask A. Endogenous endothelin-1 signaling contributes to type I collagen and CCN2 overexpression in fibrotic fibroblasts. Matrix Biol. 2007 Jun 18; [Epub ahead of print]

 

Liu S, Shi-Wen X, Kennedy L, Pala D, Chen Y, Eastwood M, Carter DE, Black CM, Abraham DJ, Leask A. FAK is required for TGF{beta] -induced phosphoylation in fibroblasts: implications for acquisition of a matrix remodeling phenotype. Mol Biol Cell. 2007 Jun;18(6):2169-2178.

 

James CG, Ulici V, Tuckermann J, Underhill TM, Beier F. Expression profiling of Dexamethasone-treated primary chondrocytes identifies targets of glucocorticoid signaling in endochondral bone development. BMC Genomics. 2007 Jul 1;8:205.

 

Appleton CT, Pitelka V, Henry J, Beier F. Global analyses of gene expression in early experimental osteoarthritis. Arthritis Rheum. 2007 Jun;56(6):1854-68

 

Kennedy L, Liu S, Shi-Wen X, Eastwood M, Carter DE, Lyons KM, Black CM, Abraham DJ, Leask A. CCN2 is necessary for the function of mouse embryonic fibroblasts. Exp Cell Res. 2007 Mar 10;313(5):952-64.

 

Agoston H, Khan S, James CG, Gillespie JR, Serra R, Stanton LA, Beier F. C-type natriuretic peptide regulates endochondral bone growth through p38 MAP kinase-dependent and independent pathways. BMC Dev Biol. 2007 Mar 20;7:18.

 

Dhaubhadel S, Gijzen M, Moy P, Farhanqkhoee M. Transciptome analysis reveals a critical role of CHS7 and CHS8 genes for isoflavonoid synthesis in soybean seeds. Plant Physiol. 2007 Jan; 143(1):326-38.

 

2006 (8)

James CG, Woods A, Underhill TM, Beier F. The transcription factor ATF3 is upregulated during chondrocyte differentiation and represses cyclin D1 and A gene transcription. BMC Mol Biol. 2006 Sept 19;7:30.

 

O'Gorman DB, Wu Y, Seney S, Zhu RD, Gan BS. Wnt Expression is not correlated with beta-catenin dysregulation in Dupuytren's Disease. J. Negat Results Biomed. 2006 Aug 30;5:13.

 

Chang WY, Andrews J, Carter DE, Dagnino L. Differentiation and injury-repair signals modulate the interaction of E2F and pRB proteins with novel target genes in Keratinocytes. Cell Cycle. 2006 Aug 15;5(16).

 

Hoffman LM, Garcha K, Karamboulas K, Cowan MF, Drysdale LM, Horton WA, Underhill TM. BMP action in skeletogenesis involves attenuation of retinoid signaling. J Cel Biol. 2006 Jul 3;174(1):101-103.

 

Shi-Wen X, Stanton L, Kennedy L, Pala D, Chen Y, Howat SL, Renzoni EA, Carter DE, Bou-Gharios G, Stratton R, Pearson JD, Beier F, Lyons KM, Black CM, Abraham DJ, Leask A. CCN2 is necessary for adhesive responses to TGFbeta 1 in embryonic fibroblasts. J Biol Chem. 2006 Apr 21;281(16):10715-26.

 

Gijzen M, Kuflu K, Moy P. Gene amplification of the Hps locus in Glycine max. BMC Plant Biol. 2006 Mar 14;6:6.

 

Gros R, Ding Q, Chorazyczewski J, Andrews J, Pickering JG, Hegele RA, Feldman RD. The impact of blunted beta-adrenergic responsiveness on growth regulatory pathways in hypertension. Mol Pharmacol. 2006 Jan;69(1):317-27.

 

Viswanathan K, Liu L, Vaziri S, Dai E, Richardson J, Togonu-Bickersteth B, Vatsya P, Christov A, Lucas AR. Myxoma viral serpin, Serp-1, a unique interceptor of coagulation and innate immune pathways. thromb Haemost. 2006 Mar;95(3):499-510.

 

2005 (7)

Mutiu AI, Brandl CJ. RNA isolation from yeast using silica matrices. J Biomol Tech. 2005 Dec; 16(4): 316-7.

 

James CG, Appleton CT, Ulici V, Underhill TM, Beier F. Microarray Analysis of Gene Expression during Chondrocyte Differentiation Identifies Novel Regulators of Hypertrophy. Mol Biol Cell. 2005 Nov;16(11):5316-33.

 

Martin MA, Bhatia M. Analysis of the Human Fetal Liver Hematopoietic Microenvironment. Stem Cells Dev. 2005 Oct 14; 14(5): 493-504.


McGirr R, Ejbick CE, Carter DE, Andrews JD, Nie Y, Friedman TC, Dhanvantari S. Glucose Dependence of the Regulated Secretory Pathway in {alpha}TC1-6 Cells. Endocrinology. 2005 Oct; 146(10):4514-23.

 

Carter DE, Robinson JF, Allister EM, Huff MW, Hegele RA. Quality assessment of microarray experiments. Clin Biochem. 2005 May 26.

 

Wang L, Menendez P, Shojaei F, Li L, Mazurier F, Dick JE, Cerdan C, Levac K, Bhatia M. Generation of hematopoietic repopulating cells from human embryonic stem cells independent of ectopic HOXB4 expression. J Exp Med. 2005 May 9.

 

Shojaei F, Trowbridge J, Gallacher L, Yuefei L, Goodale D, Karanu F, Levac K, Bhatia M. Hierarchical and ontogenic positions serve to define the molecular basis of human hematopoietic stem cell behavior. Dev Cell. 2005 May;8(5):651-63.

 

2004 (6)

Guan H, Arany E, van Beek JP, Chamson-Reig A, Thyssen S, Hill DJ, Yang K. Adipose tissue gene expression profiling reveals distinct molecular pathways that define visceral adiposity in the offspring of maternal protein restricted rats. Am J Physiol Endocrinol Metab. 2004 Nov 23.

 

McKinney JL, Murdoch DJ, Wang J, Robinson J, Biltcliffe C, Khan HM, Walker PM, Savage J, Skerjanc I, Hegele RA. Venn analysis as part of a bioinformatic approach to prioritize expressed sequence tags from cardiac libraries. Clin Biochem. 2004 Nov; 37(11):953-60.

 

Chadwick K, Shojaei F, Gallacher L, Bhatia M. Smad7 alters cell fate decisions of human hematopoietic repopulating cells. Blood. 2004 Oct 21.

 

Moy P, Qutob D, Chapman BP, Atkinson I, Gijzen M. Patterns of gene expression upon infection of Soybean plants by Phytopthora sojae. Mol Plant Microbe Interact. 2004 Oct; 17(10):1051-1062.

 

Wang L, Li L, Shojaei F, Levac K, Cerdan C, Menendez P, Martin T, Rouleau A, Bhatia M. Endothelial and hematopoietic cell fate of human embryonic stem cells originates from primitive endothelium with hemangioblastic properties. Immunity. 2004 Jul;21(1):31-41.

 

Wang J, Robinson JF, Khan HM, Carter DE, McKinney J, Miskie BA, Hegele RA. Optimizing RNA extraction yield from whole blood for microarray gene expression analysis. Clin Biochem. 2004 Sept; 37(9):741-4.

 

2003 (1)

Gris P, Murphy S, Jacob JE, Atkinson I, Brown A. Differential gene expression profiles in embryonic, adult-injured and adult-uninjured rat spinal cords. Mol Cell Neurosci. 2003 Nov;24(3):555-67.

 


Robart's Research Institute

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London Regional Cancer Centre
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Last update: Sunday, August 22, 2010